Therapeutic Effects of PPARa Agonist on Ocular Neovascularization in Models Recapitulating Neovascular Age-Related Macular Degeneration
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Citation: Qiu F, Matlock G, Chen Q, et al. Therapeutic effects of PPARa agonist on ocular neovascularization in models recapitulating neovascular agerelated macular degeneration. Invest Ophthalmol Vis Sci. 2017;58:5065– 5075. DOI:10.1167/iovs.17-22091 PURPOSE. This study was designed to evaluate effects of fenofibric acid (Feno-FA), a peroxisome proliferator–activated receptor-alpha (PPARa) agonist, on ocular neovascularization (NV) in models recapitulating neovascular age-related macular degeneration (AMD), and to explore whether the effects are PPARa dependent.
منابع مشابه
Therapeutic Effects of PPARα Agonist on Ocular Neovascularization in Models Recapitulating Neovascular Age-Related Macular Degeneration
Purpose This study was designed to evaluate effects of fenofibric acid (Feno-FA), a peroxisome proliferator-activated receptor-alpha (PPARα) agonist, on ocular neovascularization (NV) in models recapitulating neovascular age-related macular degeneration (AMD), and to explore whether the effects are PPARα dependent. Methods Laser-induced choroidal NV (CNV) in rats and very low-density lipoprot...
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تاریخ انتشار 2017